产品货号：
Z14973
中文名称：
Cyclin O/CCNO抗体
英文名称：
Anti-Cyclin O/CCNO Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Cyclin O/CCNO Antibody |
| 指标别名 | CCNU,UDG2,Cyclin-O |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB |
| 基因名称 | CCNO |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Cyclin O antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human Cyclin O.The immunogen is located within the first 50 amino acids of Cyclin O. |
| 计算分子量 | 38kDa |
| 成分 | Cyclin O Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Cyclin O Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Cyclin O,also known as CCNO,has recently been identified as a Cdk1- and Cdk2-activating cyclin specific to apoptosis in lymphoid cells.Cyclin O binds to and activates Cdk2 in response to instrinsic apoptotic stimuli such as glucocorticoids or DNA-damaging agents.Supression of Cyclin O expression by shRNA leads to the inhibition of glucocorticoid and DNA-damage-induced apoptosis due to a failure of apical caspase activation while leaving the CD95 death receptor-mediated apoptosis intact.Note:this gene,which had a previous symbol of UNG2,was erroneously identified as a uracil DNA glycosylase.A later publication identified this gene's product as a cyclin protein family member. |
| Uniprot ID | P22674 |
| 基因名全称 | Cyclin O |
| 蛋白名全称 | Cyclin O |
| 推荐稀释比 | Cyclin O antibody can be used for the detection of Cyclin O by Western blot at 1 ～ 2μg/mL.Antibody validated:Western Blot in mouse samples.All other applications and species not yet tested. |
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